If Adobe is to be believed about the reach of the Flash Player plug-in, then virtually every computer connected to the Internet is vulnerable because of this Adobe security flaw.
The good news for Firefox users is that there's a very simple way to avoid risk while we all wait on Adobe to fix their flaw and roll out an update to the billion or so people affected.
In Firefox, simply go to Tools -> Add-ons and select the Plug-ins tab. There you'll find a list of your installed Firefox plug-ins. Protecting yourself is as simple as selecting the Flash plug-in by clicking that row and then clicking the "Disable" button. (When Adobe has updated your system, you can restore Flash by repeating these instructions and clicking the "Enable" button.)